GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10935120 | 1 | rs1814337 | chr3:134200682 | ANAPC13 | chr3:134196547-134204865:- | 0.56 | 7.69 | 1.35E-11 | Height |
| THYM | cis | rs10935120 | 1 | rs1814337 | chr3:134200682 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 5.94 | 4.66E-8 | Height |
| THYM | cis | rs9457247 | 1 | rs1819333 | chr6:167373547 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs1830074 | 1 | rs1830074 | chr7:6718674 | PMS2CL | chr7:6749757-6793492:+ | -0.5 | -4.34 | 3.6E-5 | Body mass index |
| THYM | cis | rs10461617 | 1 | rs1833896 | chr5:56097669 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 9.25 | 6.53E-15 | Type 2 diabetes |
| THYM | cis | rs3820928 | 1 | rs1835158 | chr2:227763993 | RHBDD1 | chr2:227700773-227861591:+ | -0.32 | -4.73 | 7.77E-6 | Pulmonary function |
| THYM | cis | rs1577917 | 1 | rs1857964 | chr6:86635994 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs1857965 | chr6:86630776 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs10461617 | 1 | rs1862619 | chr5:56098256 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 9.25 | 6.53E-15 | Type 2 diabetes |
| THYM | cis | rs2243480 | 1 | rs186378 | chr7:65582058 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.31 | 7.1E-7 | Diabetic kidney disease |
| THYM | cis | rs10935120 | 1 | rs1863913 | chr3:134200205 | ANAPC13 | chr3:134196547-134204865:- | 0.53 | 7.15 | 1.78E-10 | Height |
| THYM | cis | rs10935120 | 1 | rs1863913 | chr3:134200205 | CEP63 | chr3:134204575-134293852:+ | 0.39 | 5.77 | 9.81E-8 | Height |
| THYM | cis | rs2564921 | 1 | rs1864367 | chr3:53111704 | RFT1 | chr3:53122503-53164470:- | -0.44 | -4.99 | 2.68E-6 | Height |
| THYM | cis | rs2742234 | 1 | rs1864395 | chr10:43655697 | CSGALNACT2 | chr10:43633934-43680747:+ | -0.34 | -4.58 | 1.44E-5 | Hirschsprung disease |
| THYM | cis | rs2742234 | 1 | rs1864399 | chr10:43610455 | CSGALNACT2 | chr10:43633934-43680747:+ | -0.34 | -4.79 | 6.22E-6 | Hirschsprung disease |